Chromosome 4P-, Wolf–Hirschhorn Syndrome

Wolf-Hirschhorn syndrome (WHS) is an extremely rare chromosomal disorder caused by a missing piece (partial deletion or monosomy) of the short arm of chromosome 4. Symptoms may include slow growth, developmental delays, cranial/facial distinctions, closure defects (including cleft lip or palate), cardiac defects, low muescle tone, kidney defects, microcephaly, and epilepsy.

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