Ichthyosis: Harlequin

Harlequin ichthyosis is a severe genetic disorder that affects the skin. Infants with this condition are born prematurely with very hard, thick skin covering most of their bodies. The skin forms large, diamond-shaped plates that are separated by deep cracks (fissures). These skin abnormalities affect the shape of the eyelids, nose, mouth, and ears, and limit movement of the arms and legs. (Medline plus)

Additional Resources

Related Albums

  • Ichthyosis is a family of genetic skin disorders characterized by dry, scaling skin that may be thickened or very thin.

  • Autosomal recessive congenital ichthyosis (ARCI) is a heterogeneous group of disorders that share an autosomal recessive pattern of inheritance, collodion [...]

  • Ichthyosis with confetti is a disorder of the skin. Individuals with this condition are born with red, scaly skin all [...]

Related FRAME Projects

  • Ichthyosis is a family of genetic skin disorders characterized by dry, scaling skin that may be thickened or very thin.