About the Images Gallery

The Positive Exposure Images Gallery  began with Rick Guidotti’s quest for a better understanding of genetic difference — and made a big splash in the world of photography. The first Positive Exposure photos appeared in a LIFE Magazine cover story entitled “Redefining Beauty,” featuring people with albinism.

Since then, Positive Exposure has photographed over 100,000 individuals at conferences, community-based initiatives, and the Gallery on NYC’s Museum Mile. Photographs have featured individuals living with a range of genetic, physical, behavioral, or intellectual difference. Ambassadors hail from everywhere in the United States and over 100 countries.

With each shoot, Positive Exposure seeks to celebrate humanity, inclusivity, and joy.
Explore the New Faces of Genetics over the years.

Note: If you’re interested in a shoot or would like to bring Positive Exposure photography to an event, reach out to us.

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  • Costello syndrome affects many different parts of the body. Signs and symptoms generally include developmental delay, intellectual disability, distinctive facial [...]

  • Cystic fibrosis (CF) is a life-threatening condition, which causes mucus buildup in the body, severely damaging the respiratory, digestive and [...]

  • DDX3X Syndrome is a rare disease caused by a spontaneous mutation within a DDX3X gene at conception or can be [...]

  • Individuals born with Down syndrome have an extra copy of chromosome 21. The presence of an extra chromosome causes mild [...]

  • Dravet syndrome, also known as Severe Myoclonic Epilepsy of Infancy (SMEI), is a rare form of intractable epilepsy that begins [...]

  • Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration and weakness due to the alterations of [...]

  • Dup15q Syndrome is a neurodevelopmental disorder characterized by having an extra copy of a portion of chromosome 15 in the [...]

  • The Ehlers-Danlos syndromes (EDS) are a group of 13 heritable connective tissue disorders. The conditions are caused by genetic changes [...]

  • Epidermolysis Bullosa, or EB, is a rare genetic connective tissue disorder that affects 1 out of every 20,000 births in [...]

  • Familial dysautonomia (FD) affects the autonomic and sensory nervous systems of children from birth. The most striking symptoms of FD [...]

  • Fragile X syndrome (FXS) is a genetic condition that causes intellectual disability, behavioral and learning challenges and various physical characteristics.

  • What is FA? Friedreich’s ataxia (FA) is a debilitating, life-shortening, degenerative neuro-muscular disorder. About one in 50,000 people in the [...]

  • Oculo-auriculo-vertebral spectrum (OAVS) refers to three rare disorders that many clinicians believe to be intimately related to one another and [...]

  • Gorlin Syndrome, also known as nevoid basal cell carcinoma syndrome (NBCCS), is a rare genetic disorder that predisposes individuals to [...]

  • Hermansky-Pudlak Syndrome (HPS) is a genetic metabolic disorder, with a prevalence of 1 to 9 in 1,000,000 individuals worldwide. It [...]

  • Hunter Syndrome (or Mucopolysaccharidosis/MPS II) is a rare condition affecting between 1 in 100,000 to 1 in 150,000 male births. [...]

  • Ichthyosis is a family of genetic skin disorders characterized by dry, scaling skin that may be thickened or very thin.

  • Autosomal recessive congenital ichthyosis (ARCI) is a heterogeneous group of disorders that share an autosomal recessive pattern of inheritance, collodion [...]

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